Aurélien Bancaud

Pulsations of engineered microvessels enhance solute clearance via heterogeneous strain-dependent poroelasticity

The paper shows pulsatile pressure in microvessels enhances solute clearance through strain-dependent poroelasticity in vascularized systems.

Monitoring the poroelastic response of collagen gels with embedded senescent fibroblasts reveals tissue softening associated with collagen network reorganization

This study uses a microfluidic model to show that senescent fibroblasts cause ECM softening through collagen network reorganization without changing permeability.

VEGF-A/C co-stimulation, without shear stress, triggers the polarization of lymphatic microvessels

This study shows that VEGF-A and VEGF-C co-stimulation induces lymphatic vessel polarization without shear stress, revealing a mechanism involving VEGFR2/VEGFR3 activation and geometrically-encoded stiffness.

Intraluminal pressure triggers a rapid and persistent reinforcement of endothelial barriers

The paper shows that intraluminal pressure rapidly strengthens endothelial barriers through actin reorganization and paracellular gap closure, lasting up to 30 minutes.

In vivo, chromatin is a fluctuating polymer chain at equilibrium constrained by internal friction

The paper models chromatin fiber dynamics in vivo, finding that transcription affects chromatin fluctuations through internal friction and transient contacts.