Author

Daniela Farchi

Emory UniversityORCID 0000-0002-0346-181XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2

Frequent Co-Authors

Anita H. CorbettiD· 2 shared Maria C. SterrettiD· 2 shared Milo B. FaskeniD· 2 shared Sarah E. StrassleriD· 2 shared Ambro van HoofiD· 1 shared Elise S. Withers· 1 shared Isaac KremskyiD· 1 shared Laurie Hess· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenetics

Anita H. CorbettORCID

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2 papers

Recent·Most cited

In vivo Characterization of the Critical Interaction between the RNA Exosome and the Essential RNA Helicase Mtr4 in Saccharomyces cerevisiae

Maria C. Sterrett, Daniela Farchi, Sarah E. Strassler, Lawrence Boise, Milo B. Fasken, Anita H. Corbett

The paper characterizes a missense mutation in EXOSC2 that affects the RNA exosome-Mtr4 interaction in yeast, showing functional consequences in RNA processing and drug sensitivity.

bioRxiv · Oct 31, 2022 · PreprintGenetics

A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome

Maria C. Sterrett, Liz Enyenihi, Sara W. Leung, Laurie Hess, Sarah E. Strassler, Daniela Farchi, Richard Sean Lee, Elise S. Withers, Isaac Kremsky, Richard E. Baker, Munira A. Basrai, Ambro van Hoof, Milo B. Fasken, Anita H. Corbett

The paper creates a yeast model of SHRF mutations in EXOSC2 and compares it to an EXOSC3 mutation model, showing distinct RNA exosome functional impacts.

RNA · Jun 23, 2021Peer-reviewedGenetics