ImmunologybioRxivPreprint
Structure-based engineering of a nutrient acquisition protein enhances neutralizing antibodies and protection for the development of a gonococcal vaccine
Natalie Y.T. Au, En Ze Linda Zhong-Johnson, Jamie E. Fegan…·Trevor F. Moraes
This study engineered a gonococcal antigen to enhance vaccine effectiveness by reducing host factor binding while maintaining structure and immunogenicity.
DOI 10.1101/2025.11.06.685839