NeurosciencebioRxivPreprint
Astrocyte fatty acid uptake and ketogenesis in the mediobasal hypothalamus coordinate adaptive metabolic responses against high-fat diet exposure in male rodents
Keila Navarro I Batista, Nadine Ellersiek, Patricia Kulka…·Christelle Le Foll
This study shows that MBH astrocyte lipid metabolism, specifically fatty acid uptake and ketogenesis, plays a key role in regulating energy balance and mitigating high-fat diet-induced obesity in male rodents.