Kirston Barton

The paper investigates how transcriptionally active HIV-1 reservoirs with APOBEC3-associated mutational signatures affect neuroaxonal integrity in individuals on suppressive antiretroviral therapy.

This study shows DNA hypomethylation disrupts replication timing precision and 3D genome organisation in colorectal cancer DNMT1 and DNMT3B knockout cells.

sangeranalyseR provides an interactive R package and Shiny apps for analyzing Sanger sequencing data, offering tools for read trimming, peak detection, and indel analysis.

This paper introduces a deep learning method for barcoding and demultiplexing direct RNA sequencing reads without base-calling or additional library steps, achieving high specificity and read demultiplexing rates.

This paper introduces RAGE-seq, a method combining long-read and short-read sequencing to analyze lymphocyte clonal and transcriptional features in breast cancer tissues.

The paper identifies novel non-coding RNAs in human brain tissue associated with neuropsychiatric traits using targeted RNA capture and long-read sequencing.

The paper demonstrates that chiral DNA sequence pairs perform equivalently in clinical genomics techniques and proposes them as commutable reference standards to improve mutation detection in tumor samples.