Matylda Macias

Phosphorylation of the AP2 μ2 subunit by p70S6 kinase facilitates clathrin-mediated endocytosis.

This study identifies that phosphorylation of AP2 μ2 subunit by p70S6 kinase modulates its conformational dynamics, enhancing clathrin-mediated endocytosis of receptors.

Rpl40/eL40 ribosomal protein paralogs couple cytosolic translation to mitochondrial proteome and lipid homeostasis

The paper investigates Rpl40 paralogs in yeast, showing they differentially affect mitochondrial proteome and lipid homeostasis under stress.

Tmbim5 and Slc8b1 cooperate in tissue-specific mitochondrial calcium regulation in zebrafish

The paper shows TMBIM5 and SLC8B1 work together in tissue-specific mitochondrial calcium regulation in zebrafish, with TMBIM5 acting as a calcium efflux pathway.

Iron deficiency drives metabolic adaptation of red pulp macrophages via ferroportin-SYK signaling and BCAA catabolism to enhance erythrophagocytosis