Author

Róża Kucharczyk

Institute of Biochemistry and Biophysics, Polish Academy of SciencesORCID 0000-0002-8712-7535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:protein structure· 1

Frequent Co-Authors

Aneta WięsykiD· 3 shared Chiranjit PanjaiD· 2 shared Marta SipkoiD· 2 shared Suchismita MasantaiD· 2 shared Abhipsita De· 1 shared Adrianna SkonecznaiD· 1 shared Agata MalinowskaiD· 1 shared Aleksandra SzybińskaiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Aneta WięsykORCID

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4 papers

Recent·Most cited

Rpl40/eL40 ribosomal protein paralogs couple cytosolic translation to mitochondrial proteome and lipid homeostasis

Kamila P. Liput, Karolina Gościńska, Monika Stasiak, Mariusz Radkiewicz, Somayeh Shahmoradi Ghahe, Katarzyna Jonak, Róża Kucharczyk, Aneta Więsyk, Eliza Molestak, Marek Tchórzewski, Matylda Macias, Aleksandra Szybińska, Ulrike Topf

The paper investigates Rpl40 paralogs in yeast, showing they differentially affect mitochondrial proteome and lipid homeostasis under stress.

bioRxiv · Jun 16, 2026 · PreprintBiochemistry

Profiling of yeast Saccharomyces cerevisiae mitochondrial AMPylome reveals a regulation of ATP synthase coupling trough subunit delta

Chiranjit Panja, Suchismita Masanta, Aneta Więsyk, Katarzyna Niedźwiecka, Emilia Baranowska, Dominik Cysewski, Marta Sipko, Anna Anielska-Mazur, Agata Malinowska, Róża Kucharczyk

The paper identifies AMPylated mitochondrial proteins in yeast, revealing a role for AMPylation in regulating ATP synthase activity and OXPHOS coupling.

bioRxiv · Dec 14, 2024 · PreprintMolecular Biology

Fmp40 ampylase regulates cell survival upon oxidative stress by controlling Prx1 and Trx3 oxidation

Suchismita Masanta, Aneta Więsyk, Chiranjit Panja, Sylwia Pilch, Jarosław Cieśla, Marta Sipko, Abhipsita De, Tuguldur Enkhbaatar, Roman Maślanka, Adrianna Skoneczna, Róża Kucharczyk

This paper identifies Fmp40 as a mitochondrial AMPylase that regulates cell survival under oxidative stress by modulating the redox states of Prx1, Trx3, and Grx2.

Redox Biology · May 21, 2024Peer-reviewedMolecular Biology

A systematic bi-genomic split-GFP assay illuminates the mitochondrial matrix proteome and protein targeting routes

Yury S. Bykov, Solène Zuttion, Dunya Edilbi, Marina Polozova, Johanna Arnold, Sergey Malitsky, Maxim Itkin, Bruno Senger, Ofir Klein, Yeynit Asraf, Hadar Meyer, Hubert D Becker, Róża Kucharczyk, Maya Schuldiner

The paper uses a bi-genomic split-GFP assay to identify mitochondrial matrix and inner membrane proteins, revealing 50 previously unvisualized proteins and characterizing dually localized proteins.

bioRxiv · Apr 17, 2024Cell Biology