Author

Laura Gennaccaro

University of BolognaORCID 0000-0002-0438-2152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alysson Renato MuotriiD· 1 shared Chiara BerteottiiD· 1 shared Elisabetta CianiiD· 1 shared Giorgio MediciiD· 1 shared Giovanna ZoccoliiD· 1 shared Giulia SagonaiD· 1 shared Giuseppe GalvaniiD· 1 shared Helen Rappe BaggettiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alysson Renato MuotriORCID

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1 paper

Recent·Most cited

EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.

Giorgio Medici, Marianna Tassinari, Giuseppe Galvani, Stefano Bastianini, Laura Gennaccaro, Manuela Loi, Nicola Mottolese, Sara Alvente, Chiara Berteotti, Giulia Sagona, Leonardo Lupori, Helen Rappe Baggett, Giovanna Zoccoli, Maurizio Giustetto, Alysson Renato Muotri, , Elisabetta Ciani

This study shows that using a secretable TATk-CDKL5 protein in AAV gene therapy improves CDKL5 replacement and functional outcomes in Cdkl5 KO mice compared to native CDKL5 expression.

bioRxiv · Jul 26, 2021 · PreprintNeuroscience