Leonardo Lupori

This study shows that electroconvulsive stimulation (ECS) in mice triggers cortical spreading depression (CSD), which increases Fos expression and is linked to positive ECT outcomes.

A single dose of clozapine in mice causes long-term behavioral and functional changes in the cortex, lasting up to 9 days, affecting specific neuron subsets and inhibitory circuits.

The paper creates a comprehensive atlas of perineuronal net distribution and colocalization with parvalbumin cells in the adult mouse brain, revealing correlations with synaptic plasticity and circuit stability.

The paper investigates how fasting-induced beta-hydroxybutyrate (BHB) affects histone modifications and gene expression in mouse brain tissue, revealing its role in modulating circadian rhythms and epigenetic landscapes.

This study shows that mGluR5 positive-allosteric modulators correct synaptic and behavioural defects in a CDKL5 deficiency disorder mouse model and human patients.

This study shows that gut microbiota changes in enriched environment mice regulate visual cortical plasticity through short-chain fatty acids.

MEYE is a web app using a Convolutional Neural Network to perform real-time pupillometry in mice and humans, offering a simple and accessible tool for non-specialists.

This study shows that using a secretable TATk-CDKL5 protein in AAV gene therapy improves CDKL5 replacement and functional outcomes in Cdkl5 KO mice compared to native CDKL5 expression.