Ernie Hwaun

Impairments in Hippocampal Place Cell Sequences during Errors in Spatial Memory

This study examines how hippocampal place cell sequences and rhythms change during memory errors in spatial tasks, finding disrupted sequence timing and replay during errors.

Re-expression of SynGAP Protein in Adulthood Improves Translatable Measures of Brain Function and Behavior in a Model of Neurodevelopmental Disorders

This study shows that restoring SynGAP protein in adult Syngap1 heterozygous mice improves memory, seizure susceptibility, and brain activity patterns.

Grid cell co-activity patterns during sleep reflect spatial overlap of grid fields during active behaviors

The paper shows that grid cell co-activity patterns during sleep reflect spatial overlap of grid fields during active behaviors, indicating recurrent connectivity drives activity across states.

CA3 place cells that represent a novel waking experience are preferentially reactivated during sharp wave-ripples in subsequent sleep

The paper shows that CA3 place cells representing novel experiences are more active during SWRs in sleep compared to those representing familiar environments.