Laura Lee Colgin

Dynamics of Dentate Gyrus Place Cells and Dentate Spikes During Spatialand Nonspatial Changes in Environments

This study examines how DG place cells and dentate spikes respond to spatial and nonspatial stimuli in familiar and novel environments, finding that nonspatial stimuli increase dentate spike activity during ethologically relevant exploration.

CA2 neurons show abnormal responses to social stimuli in a rat model of Fragile X syndrome

The paper examines CA2 neuronal responses to social stimuli in a rat model of Fragile X Syndrome and finds impaired responses despite normal social behaviors.

Hippocampal place cell sequences are impaired in a rat model of Fragile X Syndrome

This study examines how a rat model of Fragile X Syndrome affects hippocampal place cell coordination during active behavior and rest, finding impaired sequence activation and replay.

Social odors drive hippocampal CA2 place cell responses to social stimuli

This study shows that social odors specifically drive changes in hippocampal CA2 place cell firing during and after social interactions.

Impairments in Hippocampal Place Cell Sequences during Errors in Spatial Memory

This study examines how hippocampal place cell sequences and rhythms change during memory errors in spatial tasks, finding disrupted sequence timing and replay during errors.

Re-expression of SynGAP Protein in Adulthood Improves Translatable Measures of Brain Function and Behavior in a Model of Neurodevelopmental Disorders

This study shows that restoring SynGAP protein in adult Syngap1 heterozygous mice improves memory, seizure susceptibility, and brain activity patterns.

Grid cell co-activity patterns during sleep reflect spatial overlap of grid fields during active behaviors

The paper shows that grid cell co-activity patterns during sleep reflect spatial overlap of grid fields during active behaviors, indicating recurrent connectivity drives activity across states.

CA3 place cells that represent a novel waking experience are preferentially reactivated during sharp wave-ripples in subsequent sleep

The paper shows that CA3 place cells representing novel experiences are more active during SWRs in sleep compared to those representing familiar environments.