Author

Steve Niu

GenentechORCID 0000-0002-0481-7523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Abhishek Iyer· 1 shared Alberto CicciaiD· 1 shared Angelo TaglialatelaiD· 1 shared Aubrianna DeckeriD· 1 shared Ben WesleyiD· 1 shared Claudia FerraraiD· 1 shared Dan Avi LandauiD· 1 shared Edmond M. ChaniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Abhishek Iyer

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Vascularized tumor organoids enable immunotherapy testing in tumor-remodeled stroma

Reiner Wimmer, Rok Krese, Louisa Henniger, Steve Niu, Nadege Lagarde, Timon Keller, Inga Clausen, Fabian Köchel, Claudia Ferrara, Inja Waldhauer, Marina Bacac, Nikolche Gjorevski, Fjodor Melnikov, Rémi Villenave

This paper introduces vascularized tumor organoids (VascO) to model tumor microenvironments for immunotherapy testing, showing they can assess drug safety and efficacy in a patient-specific context.

bioRxiv · Jan 26, 2026 · PreprintBioengineering

CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue

Jiacheng Gu, Abhishek Iyer, Ben Wesley, Angelo Taglialatela, Giuseppe Leuzzi, Sho Hangai, Aubrianna Decker, Ruoyu Gu, Naomi Klickstein, Yuanlong Shuai, Kristina Janković, Lucy Parker-Burns, Yinuo Jin, Jia Yi Zhang, Justin Hong, , Jellert T. Gaublomme

CRISPRmap enables multi-omic optical pooled screens to map gene function in cells and tissue without sequencing, identifying pathogenic mutations and analyzing spatial phenotypes.

bioRxiv · Dec 26, 2023 · PreprintGenomics