Author

Umme H Faisal

Northwestern UniversityORCID 0000-0002-0486-2391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam M. SonabendiD· 2 shared Hasaan A Kazi· 2 shared Lara KoutahiD· 2 shared Maeve C. O’Shea· 2 shared Noah B. DrewesiD· 2 shared Rafał ChojakiD· 2 shared A. Karim AhmediD· 1 shared Alicia Catezone· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Adam M. SonabendORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Temozolomide-associated inflammatory-repair remodeling in recurrent glioblastoma exposes a ROCK-linked therapeutic vulnerability

Rafał Chojak, Umme Habiba Faisal, Priya Kumthekar, Noah B. Drewes, Lara Koutah, Jessica Jia, Jillyn R Turunen, Maeve C. O’Shea, Victoria Falkowski, Ayaan Akhtar, Shu Wang, Justin Chen, Shanti Ahmed, Hasaan A Kazi, Brenda Auffinger, , Atique U. Ahmed

This study shows that preoperative temozolomide exposure in recurrent glioblastoma leads to inflammatory-repair remodeling and a ROCK-linked therapeutic vulnerability, which can be targeted by fasudil.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

THOC1 complexes with SIN3A to regulate R-loops and promote glioblastoma progression

Shreya Budhiraja, Umme H Faisal, Shivani Baisiwala, Rafał Chojak, Lara Koutah, Noah B. Drewes, Sia Cho, Hasaan A Kazi, Rebecca Chen, Ella N. Perrault, Li Chen, Cheol H. Park, Maeve C. O’Shea, Khizar Rehan Nandoliya, Joseph T. Duffy, , A. Karim Ahmed

This study identifies THOC1 as a driver of glioblastoma progression by interacting with SIN3A to regulate R-loops and telomere stability.

Neoplasia · Jan 6, 2026Peer-reviewedCancer Biology