ImmunologyScience AdvancesPeer-reviewed
A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes
Matthew J. Witney, Nathan P. Croft, Michael Yik-Chun Wong…·David C. Tscharke
This study quantifies antigen presentation kinetics and immunogenicity of viral epitopes during poxvirus infection, revealing that epitope levels correlate with immunogenicity only when measured ex vivo.