Nicole L. La Gruta

The paper identifies a novel HLA-DR15-restricted CD4 T cell epitope from PR3 associated with vasculitis and describes its unconventional presentation mechanism.

This study quantifies antigen presentation kinetics and immunogenicity of viral epitopes during poxvirus infection, revealing that epitope levels correlate with immunogenicity only when measured ex vivo.

The paper identifies transcriptional modules and cytokine signaling pathways that drive functional heterogeneity in T follicular helper cells across different infections.

This study identifies SATB1 as a regulator that maintains naive CD8+ T cell identity by restricting chromatin remodelling at effector gene loci, preventing premature differentiation during viral infection.

TCR_Explore is a webtool for TCR repertoire analysis that automates quality control and analysis, enabling non-expert users to generate publication-ready figures.