Author

Nathan P. Croft

Monash UniversityORCID 0000-0002-2128-5127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anthony Wayne PurcelliD· 3 shared Nicole A. MifsudiD· 2 shared A. K. M. MuraduzzamaniD· 1 shared Alexandra GrubmaniD· 1 shared Aly FayediD· 1 shared Anthony W. Pumassmrcell· 1 shared Asolina BrauniD· 1 shared Beatrice Dyring‐AnderseniD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

Anthony Wayne PurcellORCID

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Author profile →

4 papers

Recent·Most cited

Identification of HLA-A33-restricted CD8+ T cell epitopes from avian influenza A/H5N1

A. K. M. Muraduzzaman, Patricia T. Illing, Mitchell Jenzen, Nathan P. Croft, Sinéad M. Williams, Paul Selleck, Michelle L. Baker, Katherine Kedzierska, Anthony Wayne Purcell, Nicole A. Mifsud

Immunopeptidomics shows HLA-A*33:01 and HLA-A*33:03 present largely distinct influenza peptide repertoires, and four HLA-A*33:03-restricted epitopes triggered CD8+ T cell responses in A/H5N1-naive donors.

bioRxiv · Jul 13, 2026 · PreprintImmunology✦ In-depth digest

Immunopeptidomics reveals peptide antigens preferentially presented in psoriasis lesional skin of HLA-C*06:02 carriers

Bjørn Kromann Hansen, Shanzou Chung, Prithvi Raj Munday, Jingran Ye, Chen Li, Nathan P. Croft, Nicole A. Mifsud, Michael Bzorek, Varun J. Sharma, Aly Fayed, Graham Starkey, Rohit D’Costa, Claire L. Gordon, Morten Bahrt Haulrig, Thuvarahan Jegathees, , Asolina Braun

The paper identifies HLA-C*06:02-presented peptides in psoriasis lesions, finding lesion-specific peptides linked to disease pathogenesis.

bioRxiv · Jan 26, 2026 · PreprintImmunology

A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes

Matthew J. Witney, Nathan P. Croft, Michael Yik-Chun Wong, Stewart A. Smith, Inge E. A. Flesch, E. Keller, Leon C. W. Lin, Yanli Li, Nicole L. La Gruta, Anthony Wayne Purcell, David C. Tscharke

This study quantifies antigen presentation kinetics and immunogenicity of viral epitopes during poxvirus infection, revealing that epitope levels correlate with immunogenicity only when measured ex vivo.

Science Advances · Dec 19, 2025Peer-reviewedImmunology

Mouse and human microglial phenotypes in Alzheimer’s disease are controlled by amyloid plaque phagocytosis through Hif1α

Alexandra Grubman, Xin Yi Choo, Gabriel Chew, John F. Ouyang, Guizhi Sun, Nathan P. Croft, Fernando Jaime Rossello, Rebecca K. Simmons, Sam Buckberry, Dulce B. Vargas-Landín, Jahnvi Pflueger, Teresa H. Vandekolk, Zehra C. Abay, Xiaodong Liu, John M. Haynes, , Jose Maria Polo

This study identifies that amyloid plaque phagocytosis through Hif1α controls microglial phenotypes in Alzheimer’s disease in both mice and humans.

bioRxiv · May 17, 2019 · PreprintNeuroscience