William Edward Louch

This study investigates the role of ER calcium stores in glucose-induced Ca2+ waves and intercellular connectivity in mouse pancreatic islets, finding that ER mobilization is insufficient to initiate waves but required for sustained waves and connectivity.

This study shows that reduced gap junction coupling between cardiomyocytes amplifies cellular variability and leads to arrhythmias by causing nonhomogeneous action potentials and early after-depolarizations.

This study uses computational models to show female atrial cardiomyocytes in AF have higher Ca2+-driven arrhythmia risk than males, with specific interventions identified to address these differences.

This study shows that disrupting the TARP-ARC interaction stabilizes synaptic AMPA receptors and rescues fear memory deficits caused by social isolation in mice.