Author

Aamra Mahboob

MRC Laboratory of Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Clive R. BramhamiD· 2 shared Aditya PokharnaiD· 1 shared Adrian SzumiD· 1 shared Adriana MagalskaiD· 1 shared Andrzej Antoni SzczepankiewicziD· 1 shared Dagmara Holm-KaczmarekiD· 1 shared Erik Ingmar HalliniD· 1 shared François Philippe PauziniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Clive R. BramhamORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Arc/Arg3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles

Tambudzai Kanhema, Kamil Parobczak, Sudarshan S. Patil, Dagmara Holm-Kaczmarek, Erik Ingmar Hallin, Jan Ludwiczak, Andrzej Antoni Szczepankiewicz, François Philippe Pauzin, Aamra Mahboob, Adrian Szum, Yuta Ishizuka, Stanisław Dunin-Horkawicz, Petri Kursula, Grzegorz Marek Wilczynski, Adriana Magalska, Clive R. Bramham

This study identifies Arc/Arg3.1 as a regulator of PABPN1 nuclear speckles through direct binding, impacting mRNA processing during neuronal activity.

Cell Reports · Apr 1, 2025Peer-reviewedNeuroscience

Disruption of TARP-ARC interaction stabilizes synaptic AMPA receptors and rescues social isolation-induced fear memory deficits

Jens Edvard Trygstad Gundersen, Xinrong Wu, Jiaxing Song, Aditya Pokharna, Lorena Benedetti, Aamra Mahboob, Håvard Håvardsholm Nesbø, Tadiwos Feyissa Mergiya, William Edward Louch, Huadong Liu, Suya Sun, Jennifer Lippincott‐Schwartz, Ingo H. Greger, Nan‐Jie Xu, Clive R. Bramham, Hongyu Zhang

This study shows that disrupting the TARP-ARC interaction stabilizes synaptic AMPA receptors and rescues fear memory deficits caused by social isolation in mice.

bioRxiv · Aug 4, 2024 · PreprintNeuroscience