Xinrong Wu

This study shows that disrupting the TARP-ARC interaction stabilizes synaptic AMPA receptors and rescues fear memory deficits caused by social isolation in mice.

This study identifies a specific LEC-vCA1 pathway that uses low gamma-band oscillations to facilitate fear extinction and shows its therapeutic potential through DBS and tACS in a PTSD mouse model.

The paper shows that forgetting of extinction memory involves a dynamic shift in the connectivity of engram circuits between the mPFC, BLA, and vHPC.