A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
Emily L. Ashkin, Yuning J. Tang, Haiqing Xu, King L. Hung, Julia A. Belk, Hongchen Cai, Steven S. Lopez, Deniz Nesli Dolcen, Jess D. Hebert, Rui Li, Paloma A. Ruiz, Tula Keal, Laura Andrejka, Howard Y. Chang, Dmitri A. Petrov, , Monte M. Winslow
This study identifies a STAG2-PAXIP1/PAGR1 tumor-suppressive axis in lung cancer by showing their combined role in suppressing oncogenic KRAS-driven tumorigenesis.
The Journal of Experimental Medicine · Oct 31, 2024Peer-reviewedCancer Biology