Christine M. Seroogy

Farm exposure is associated with human breast milk immune profile and microbiome

The paper compares immune profiles and microbiomes of breast milk from mothers with different farm exposures to identify associations with immune development and atopic disease.

Altered Purinergic Signaling and CD8+ T Cell Dysregulation in STAT3 GOF Syndrome

This study identifies altered purinergic signaling and CD8+ T cell dysregulation in STAT3 GOF syndrome, showing partial normalization with JAK inhibitors.

Exclusive liquid repellency isolation (ELRi) microliter scale isolation technique unmasks T-cell migration defects to CCL21 in pediatric asthma

ELRi isolates immune cells from small blood samples, revealing impaired T-cell migration to CCL21 in pediatric asthma.

Selection of Genetic Conditions for Multi-State Genomic Newborn Screening in BEACONS-NBS

The paper develops a comprehensive list of genetic conditions for genomic newborn screening, including 777 conditions associated with 743 genes, for implementation across multiple U.S. states and territories.

Upper respiratory microbial communities of healthy populations are shaped by niche and age

This study compares nasal and oral microbiomes of infants and adults, finding age-related differences in diversity, composition, and functional capabilities.