Subashika Govindan

Neuro-toxicogenomic mapping of TMT induced neurotoxicity using human minibrain reveals associated adverse outcome events

This study uses human minibrain models and BRB-seq to analyze TMT-induced neurotoxicity, identifying key molecular events and pathways involved in adverse outcomes.

Mass Generation, Neuron Labelling and 3D Imaging of Minibrains

This study presents methods to generate and label human minibrains for large-scale 3D imaging and cell type analysis.

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

This study investigates how OCT4 and SOX2 regulate chromatin accessibility in mouse embryonic stem cells across the cell cycle, showing their independent and cooperative roles in maintaining pluripotency.

Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

The paper shows that fluctuations in OCT4 and SOX2 levels influence cell fate decisions by affecting chromatin accessibility at differentiation enhancers.

In vivo pulse-labeling of isochronic cohorts of cells in the central nervous system using FlashTag

This paper describes a protocol for in vivo pulse-labeling of newborn cells in the central nervous system using carboxyfluorescein esters, enabling tracking and isolation for downstream analysis.