Hamilton White

This study uses C. elegans to show that isoflurane induction causes gradual neuronal disconnection and disorganization, reversing the dynamics seen during emergence from anesthesia.

The paper develops a mathematical framework to explain how neural adaptation in C. elegans leads to flexible behavioral responses, including habituation and paradoxical inversion.

This study investigates ketamine's effects on neuronal activity in C. elegans, finding it induces global excitatory network oscillations by decoupling key interneurons.