Author

Ritu Gupta

National Institutes of HealthORCID 0000-0002-0563-6599Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 4 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Sunil LaxmaniD· 3 shared Swagata AdhikaryiD· 2 shared Adhish S. WalvekariD· 1 shared Alan G. HinnebuschiD· 1 shared Christopher G. TateiD· 1 shared Mary Talatu AnganiiD· 1 shared Nidhi DalpatrajiD· 1 shared Rajalakshmi SrinivasaniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersSystems Biology

Sunil LaxmanORCID

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Author profile →

4 papers

Recent·Most cited

Rad53/Chk2 couples mitochondrial outputs and ROS with G2/M cell cycle progression

Swagata Adhikary, Ritu Gupta, Vineeth Vengayil, Sunil Laxman

This study shows Rad53/Chk2 links mitochondrial function and ROS levels to G2/M cell cycle progression in yeast.

bioRxiv · Oct 16, 2026 · PreprintCell Biology

Molecular Architecture of the Human GCN1-ABCF3 Ribosome Collision Sensor

Viswanathan Chandrasekaran, Ritu Gupta, Mary Talatu Angani, Talal F. M. Haddad, Christopher G. Tate, Venki Ramakrishnan, Alan G. Hinnebusch

This study identifies ABCF3 as the mammalian ortholog of yeast Gcn20, which is recruited to ribosomes during amino acid starvation and interacts with GCN1 to activate Gcn2.

bioRxiv · Sep 22, 2026 · PreprintBiochemistry

A demand-based framework explains prioritization strategies upon transient limitations of different amino acids.

Ritu Gupta, Swagata Adhikary, Nidhi Dalpatraj, Sunil Laxman

The paper shows cells prioritize restoring amino acids based on demand and biosynthetic cost, with arginine being the highest priority.

Nature Communications · Aug 23, 2024Peer-reviewedSystems Biology

Methionine coordinates a hierarchically organized anabolic program enabling proliferation.

Adhish S. Walvekar, Rajalakshmi Srinivasan, Ritu Gupta, Sunil Laxman

The paper identifies how methionine reprograms yeast metabolism to support proliferation by rewiring key metabolic pathways and co-opting a stress response regulator.

Molecular Biology of the Cell · Oct 24, 2018Peer-reviewedSystems Biology