Rasmus Kjøbsted

The paper uses personalized phosphoproteomics to show that mTORC1 regulates exercise-induced insulin sensitization in human skeletal muscle through a feedback pathway involving MKNK2 and eIF4G1.

This study investigates the AMPKgamma3 R225W mutation in human and mouse skeletal muscle, finding no increase in basal activity or glycogen levels, but loss of activation by AICAR/muscle contraction.

The paper develops a high-throughput workflow for subcellular proteome and phospho-proteome profiling and applies it to study EGFR signaling and stress responses in cells.