ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A2A adenosine receptor
Ivan Maslov, Valentin I. Borshchevskiy, Iván Pérez, Vadim Cherezov, Johan Hofkens, Jelle Hendrix, Michael Börsch, Thomas Gensch
This study uses ABEL-FRET to measure structural dynamics of A2A adenosine receptors across timescales, showing agonists shift receptor states and accelerate conformational exchange.
Communications Chemistry · Mar 9, 2026Peer-reviewedBiophysics