A Structure-Based Mechanism for DNA Entry into the Cohesin Ring
Torahiko L. Higashi, Patrik Eickhoff, Joana S. Sousa, Julia Locke, Andrea Nans, Helen R. Flynn, Ambrosius P. Snijders, George Papageorgiou, Nicola O’Reilly, Zhuo Angel Chen, Francis J. O’Reilly, Juri Rappsilber, Alessandro Costa, Frank Uhlmann
This study uses cryo-EM and biochemical experiments to reveal the mechanism of DNA entry into the cohesin ring, showing how ATP binding and hydrolysis regulate the process.
Molecular Cell · Aug 4, 2020Peer-reviewedMolecular Biology