Matthijs M. Jore

Controlled human infection with Plasmodium falciparum-infected mosquito bites elicits antibodies against mosquito salivary protein SG1L3

The paper identifies human antibodies against a mosquito salivary protein, SG1L3, that binds to Plasmodium falciparum sporozoites but does not block infection.

Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate

This study identifies Pfs230 Domain 12 as a potent malaria transmission-blocking vaccine candidate that induces antibodies reducing parasite transmission to mosquitoes.

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies

The paper determines the structure of the Pfs230:Pfs48/45 complex bound to transmission-blocking antibodies, revealing molecular interactions and epitopes that inform vaccine development.