Author

Danton Ivanochko

Great Ormond Street HospitalORCID 0000-0002-2826-8100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein structure prediction· 3 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jean‐Philippe JulieniD· 3 shared John L. RubinsteiniD· 2 shared Amrita Dhindsa· 1 shared Ayana Maeda· 1 shared Brian CoventryiD· 1 shared Carolina M. AndradeiD· 1 shared David A. BakeriD· 1 shared Eizo TakashimaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Jean‐Philippe JulienORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systems-Scale Structural Modeling Reveals the Germline Architecture of Immunodominance

Ellen L. Shrock, Eric Sun, Amrita Dhindsa, Max H. Witwer, Zhou Yu, Danton Ivanochko, I‐Hsiu Lee, Brian Coventry, Maria Borras Gonzalez, Jean‐Philippe Julien, Stephen Joseph Elledge, David A. Baker

This study identifies germline-encoded features as the primary driver of immunodominance in antibody responses to SARS-CoV-2, using structural modeling and mutational analysis.

bioRxiv · Jun 4, 2026 · PreprintImmunology

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies

Ezra T. Bekkering, Randy Yoo, Sophia Hailemariam, Fabian Heide, Danton Ivanochko, Matthew J. Jackman, Nicholas I. Proellochs, Rianne Stoter, Geert-Jan van Gemert, Ayana Maeda, Takaaki Yuguchi, Oscar T. Wanders, Renate C. van Daalen, Maartje R. Inklaar, Carolina M. Andrade, , Jean‐Philippe Julien

The paper determines the structure of the Pfs230:Pfs48/45 complex bound to transmission-blocking antibodies, revealing molecular interactions and epitopes that inform vaccine development.

bioRxiv · Feb 14, 2025 · PreprintMolecular Biology

Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats

Iga Kucharska, Lamia Hossain, Danton Ivanochko, Qiren Yang, John L. Rubinstein, Régis Pomès, Jean‐Philippe Julien

This study reveals the structural basis of Plasmodium vivax inhibition by antibodies targeting the CSP repeats through molecular dynamics simulations and crystal structure analysis of inhibitory monoclonal antibodies.

eLife · Jan 13, 2022Peer-reviewedMolecular Biology