Anopheles mosquitoes exposed to long-acting antimalarials via drug-spiked bloodmeal absorb drug but do not suffer fitness costs
Morgan M. Goheen, Alessandra Silva Orfano, Sié Rodrigue Dah, Brian D. Foy, Doug E. Brackney, Fangyong Li, Jean‐Bosco Ouédraogo, Dari Frédéric Da, Roch K. Dabiré, Anyirékun Fabrice Somé, Amy Kristine Bei, Sunil Parikh
This study shows Anopheles mosquitoes absorb long-acting antimalarials from bloodmeals but do not experience fitness costs, with drug detected in hemolymph and midguts.
bioRxiv · Nov 13, 2025 · PreprintMicrobiology