Michela Dell’Orco

This study identifies gene expression changes in brain tissue following spreading depolarization, showing activation of pathways related to cell differentiation, synaptic plasticity, and neuroprotection.

This study identifies KHSRP as an axonal RNA-binding protein whose mRNA is locally translated after nerve injury, leading to mRNA destabilization and slowed axon regeneration.

The paper compares RNA profiles in plasma-derived large and small extracellular vesicles from neurodegenerative disease patients and healthy controls, identifying disease-specific miRNA signatures.