Author

Andromachi Papagiannoula

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0000-0002-0767-5129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:protein structure· 1

Frequent Co-Authors

Sigrid MillesiD· 2 shared Advika Kamatar· 1 shared Arbesa Saiti· 1 shared Brandon T. MaladyiD· 1 shared Carl C. Hayden· 1 shared David J. OweniD· 1 shared Eileen M. LaferiD· 1 shared Gavin T. Lebrun· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Sigrid MillesORCID

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2 papers

Recent·Most cited

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

Brandon T. Malady, Andromachi Papagiannoula, Advika Kamatar, Susovan Sarkar, Gavin T. Lebrun, Liping Wang, Carl C. Hayden, Eileen M. Lafer, David J. Owen, Sigrid Milles, Jeanne C. Stachowiak

This study shows that protein condensates and clathrin assembly regulate each other during clathrin-mediated endocytosis, enhancing vesicle formation while controlling condensate growth.

Nature Communications · Oct 15, 2025Peer-reviewedBiophysics

Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network.

Andromachi Papagiannoula, Ida Marie Vedel, Kathrin Motzny, Maud Tengo, Arbesa Saiti, Sigrid Milles

The paper investigates Eps15's EH domains interactions with Dab2 and its own IDR, revealing promiscuous binding and a self-inhibitory mechanism that facilitates endocytosis.

Nature Communications · Aug 21, 2025Peer-reviewedBiophysics