Marleen E Jacobs

COAST aligns consecutive tissue sections using only spatial images, enabling unified multi-modal molecular data analysis without molecular markers or annotations.

This paper introduces a quantitative MSI workflow using 13C-labeled yeast extract to enable reliable spatial metabolomics, revealing metabolic changes in the ipsilateral cortex after stroke.

This study shows that normothermic kidney preservation with red blood cells causes iron accumulation and ferroptosis, leading to kidney injury, and suggests alternatives to mitigate these effects.