Author

Sarantos Kostidis

Leiden University Medical CenterORCID 0000-0002-2040-2563Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Organism:C. elegans· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Martin A. GieraiD· 2 shared Arnoud H. de RuiD· 1 shared Arthur LiesziD· 1 shared Augustinus N. A. AmmerlaaniD· 1 shared Bernard M. van den BergiD· 1 shared Bob van PuffeleniD· 1 shared Dmitri V. FilippoviD· 1 shared Gangqi WangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Martin A. GieraORCID

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2 papers

Recent·Most cited

Identification of novel cellular intermediates unveils unique enzymes for flagellar glycan biosynthesis in Clostridioides difficile

Paul J. Hensbergen, Bob van Puffelen, Nina Musch, Augustinus N. A. Ammerlaan, P. Zuidgeest, Loes van Huijkelom, Rembrandt J.V. Kanbier, Maaike M. Vet, Xuan S. Zheng, Pranav V.N. Bhamidipati, Martin F. Larralde, Niek Blomberg, Sarantos Kostidis, Peter A. van Veelen, Robert A. Cordfunke, , Jeroen Corver

This study identifies two novel biosynthetic intermediates and characterizes their enzymes in the unique glycan modification pathway of C. difficile flagellin.

Proceedings of the National Academy of Sciences · Jul 7, 2026Peer-reviewedMicrobiology

Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke

Gangqi Wang, Bernard M. van den Berg, Sarantos Kostidis, Kelsey Pinkham, Marleen E Jacobs, Arthur Liesz, Martin A. Giera, Ton J. Rabelink

This paper introduces a quantitative MSI workflow using 13C-labeled yeast extract to enable reliable spatial metabolomics, revealing metabolic changes in the ipsilateral cortex after stroke.

Nature Metabolism · Aug 5, 2025Peer-reviewedBiochemistry