Petros Kolovos

Two distinct chromatin modules regulate proinflammatory gene expression

The paper identifies two chromatin modules, ACs and DCs, that regulate proinflammatory gene expression through distinct mechanisms in human endothelial cells.

Serotonin attenuates tumor-necrosis-factor-alpha-induced intestinal inflammation by interacting with human mucosal tissue

This study shows serotonin reduces inflammation in intestinal tissue by altering monocyte behavior and chemokine expression using a human 3D model.

Chromatin architecture and cis-regulatory landscape of the DACT2-SMOC2 locus in the developing synovial joint.

The paper investigates the cis-regulatory landscape of DACT2 and SMOC2 in developing synovial joints using chromatin capture and enhancer assays.

Genome-wide Association Study identifies two novel loci for Gilles de la Tourette Syndrome

This study identifies two novel genetic loci associated with Tourette Syndrome through a genome-wide meta-analysis and integrates functional data to implicate specific genes.

The Detailed 3D Multi-Loop Aggregate/Rosette Chromatin Architecture and Functional Dynamic Organization of the Human and Mouse Genomes

This paper describes the 3D chromatin architecture of human and mouse genomes at multiple scales, showing its dynamic organization and co-evolution with DNA sequence.