Author

Varun Bahl

University of PennsylvaniaORCID 0000-0002-0789-8613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Klaus H. KaestneriD· 2 shared Michelle Y. Y. LeeiD· 2 shared Benjamin F. VoightiD· 1 shared Benjamin GläseriD· 1 shared Catherine Lee May· 1 shared Dana AvrahamiiD· 1 shared Daniel TraumiD· 1 shared Elisabetta ManduchiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Klaus H. KaestnerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

G6PC2 controls glucagon secretion by defining the setpoint for glucose in pancreatic α-cells

Varun Bahl, Eric Waite, Reut Rifkind, Zenab Hamdan, Catherine Lee May, Elisabetta Manduchi, Benjamin F. Voight, Michelle Y. Y. Lee, Mark Tigue, Nicholas Manuto, Benjamin Gläser, Dana Avrahami, Klaus H. Kaestner

This study identifies G6PC2's role in regulating glucagon secretion in α-cells, showing it controls glucose setpoint and suggests G6PC2 inhibitors could improve glycemic control.

Science Translational Medicine · Jan 1, 2025Peer-reviewedGenetics

Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry

Minghui Wu, Michelle Y. Y. Lee, Varun Bahl, Daniel Traum, Jonathan Schug, Irina Kusmartseva, Mark A. Atkinson, Guanjie Fan, Klaus H. Kaestner

This study uses imaging mass cytometry to analyze pancreatic cells in T2D patients and controls, revealing changes in islet structure, cell composition, and immune cell infiltration.

Cell Reports · Nov 1, 2021Peer-reviewedMolecular Biology