This study investigates mpox virus transmission in prairie dogs, finding that anogenital mucosal routes lead to high shedding and efficient transmission.

bioRxiv · Aug 14, 2025 · PreprintMicrobiology

Increased contact transmission of contemporary Human H5N1 compared to Bovine and Mountain Lion H5N1 in a hamster model

Reshma Koolaparambil Mukesh, Franziska Karola Kaiser, Jonathan E. Schulz, Shane Gallogly, Jessica Prado-Smith, Arthur Wickenhagen, Kathleen Cordova, Brian J. Smith, Chad S. Clancy, Carl Shaia, Greg A. Saturday, Emmie de Wit, Neeltje van Doremalen, Claude Kwe Yinda, Vincent Jacobus Munster

The study compares contact transmissibility of human, bovine, and mountain lion H5N1 isolates in Syrian hamsters, finding human isolate has higher contact transmissibility despite limited overall transmission.

bioRxiv · Jun 23, 2025 · PreprintMicrobiology

Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice

Kerry Goldin, Sarah van Tol, Randall C. Johnson, Reshma Koolaparambil Mukesh, Kendal G. Cooper, Shane Gallogly, Jonathan E. Schulz, Jessica Prado-Smith, Craig Martens, Greg A. Saturday, Claude Kwe Yinda, Vincent Jacobus Munster, Emmie de Wit, Neeltje van Doremalen

This study compares the tissue tropism of two HPAI H5N1 isolates in mice, finding that the bovine isolate replicates in the brain and causes more neurotropism and inflammation than the human isolate.

npj Viruses · May 23, 2025Peer-reviewedMicrobiology

Jamaican fruit bats (Artibeus jamaicensis) competence for Ebola virus but not Marburg virus is driven by intrinsic differences in viral entry and IFN-I signaling antagonism.

Sarah van Tol, Julia Rebecca Port, Robert J. Fischer, Shane Gallogly, Trenton Bushmaker, Amanda Griffin, Jonathan E. Schulz, Aaron Carmody, Lara M. Myers, Daniel E. Crowley, Caylee Falvo, Jade C. Riopelle, Arthur Wickenhagen, Chad S. Clancy, Jamie Lovaglio, , Vincent Jacobus Munster

This study shows Jamaican fruit bats can support EBOV replication and shedding but not MARV, due to differences in viral entry and IFN-I signaling suppression.

Nature Communications · Mar 25, 2025Peer-reviewedImmunology