Chad S. Clancy

This study shows Jamaican fruit bats are susceptible to henipaviruses but rapidly control infection following oral exposure.

A single-dose VSV-BDBV vaccine protects macaques from BDBV challenge within 3 days by inducing neutralizing antibodies and Fc effector function.

This study identifies antibody avidity as a correlate for in vivo efficacy of broadly reactive anti-alphavirus antibodies and links it to Fc-dependent mechanisms.

This study compares the virulence of recent bovine and non-bovine HPAI H5N1 isolates in mice, finding the bovine isolate causes severe respiratory and neurologic disease.

The study compares contact transmissibility of human, bovine, and mountain lion H5N1 isolates in Syrian hamsters, finding human isolate has higher contact transmissibility despite limited overall transmission.

A single dose of VSV-SUDV vaccine protected macaques from lethal SUDV infection within one week, while VSV-EBOV provided no cross-protection.

This study shows Jamaican fruit bats can support EBOV replication and shedding but not MARV, due to differences in viral entry and IFN-I signaling suppression.