Author

Ryan Ramsey Hosn

Columbia UniversityORCID 0000-0002-0818-8031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Artemis MargaronisiD· 1 shared Bridget Li· 1 shared Byungji KimiD· 1 shared Claire Wu· 1 shared Darrell J. IrvineiD· 1 shared Ethan KrissiD· 1 shared Howard H. MakiD· 1 shared Jae Yun JeongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Artemis MargaronisORCID

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2 papers

Recent·Most cited

Supramolecular hydrogel viscoelasticity regulates in situ tertiary lymphoid neogenesis

Ryan Ramsey Hosn, Oriana Marrone Mantovani, Artemis Margaronis, James S. Wang, Ethan Kriss, Claire Wu, Michael D. Kissner, José L. McFaline‐Figueroa, Santiago Correa

This study shows that soft hydrogels promote tertiary lymphoid structure formation, while stiff hydrogels hinder it, improving antitumor immunity.

bioRxiv · Jul 21, 2026 · PreprintBioengineering

Targeted suppression of type 1 interferon signaling during RNA delivery enhances vaccine-elicited immunity

Byungji Kim, Ryan Ramsey Hosn, Tanaka K. Remba, Jonathan Dye, Howard H. Mak, Jae Yun Jeong, Milton R. Cornwall-Brady, Wuhbet D. Abraham, Laura Maiorino, Mariane B. Melo, Bridget Li, Yuebao Zhang, Yizhou Dong, Darrell J. Irvine

This study shows that co-delivering siRNA targeting IFNAR1 with RNA vaccines enhances antigen expression, immune cell infiltration, and antibody and T cell responses.

bioRxiv · Mar 9, 2025 · PreprintBioengineering