Howard H. Mak

This paper develops an in vivo method to covalently link peptide drugs to native IgGs, demonstrating sustained weight loss and glucose management with GLP-1.

This study shows that co-delivering siRNA targeting IFNAR1 with RNA vaccines enhances antigen expression, immune cell infiltration, and antibody and T cell responses.

This study visualizes lipid nanoparticle trafficking in non-human primates using PET imaging, showing distribution to muscle and draining lymph nodes with uptake by antigen-presenting cells.