Author

Nareg Pinarbasi Degirmenci

Koç UniversityORCID 0000-0002-3366-145XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Approach:statistical model· 2 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Tugba Bagci OnderiD· 4 shared Adam P. CribbsiD· 3 shared Udo C. T. OppermanniD· 3 shared Buse CevatemreiD· 2 shared Ceyda AçılaniD· 2 shared Martin PhilpottiD· 2 shared Nathan A. LackiD· 2 shared Ahmet CingöziD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

Tugba Bagci OnderORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BRD9 inhibition induces selective radiosensitivity in glioblastoma through MYC pathway modulation

Nareg Pinarbasi Degirmenci, S A Celikkol, Beyza Nur Köseoğlu, Adam P. Cribbs, Udo C. T. Oppermann, Uğur Selek, Tugba Bagci Onder

This study identifies BRD9 inhibition as a strategy to enhance radiosensitivity in glioblastoma by modulating the MYC pathway, without significant cytotoxicity under normal conditions.

bioRxiv · Aug 11, 2026 · PreprintCancer Biology

Chemical screens identify HDAC6 as an epigenetic vulnerability in acquired Temozolomide-resistant models of glioblastoma

Feridun Aksu, Buse Cevatemre, Nareg Pinarbasi Degirmenci, Ezgi Yağmur Kala, Duygu Uçku, Martin Philpott, Adam P. Cribbs, James E. Dunford, Udo C. T. Oppermann, Ceyda Açılan, Tugba Bagci Onder

The paper identifies HDAC6 as an epigenetic vulnerability in TMZ-resistant glioblastoma models and shows HDAC6 inhibitors can restore TMZ sensitivity.

bioRxiv · May 11, 2026 · PreprintCancer Biology

Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer

Ozlem Yedier-Bayram, Ahmet Cingöz, Ebru Yilmaz, Ali Cenk Aksu, Beril Esin, Nareg Pinarbasi Degirmenci, Ayşe Derya Cavga, Beyza Dedeoğlu, Buse Cevatemre, Hamzah Syed, Martin Philpott, Adam P. Cribbs, Udo C. T. Oppermann, Nathan A. Lack, Ceyda Açılan, , Tugba Bagci Onder

The paper identifies BRPF1 as a key regulator of Taxol resistance in TNBC through genetic and chemical screens, showing its inhibition sensitizes resistant cells to chemotherapy.

Experimental & Molecular Medicine · Jun 29, 2025Peer-reviewedCancer Biology

Protein scaffold-based multimerization of soluble ACE2 efficiently blocks SARS-CoV-2 infection in vitro and in vivo

Alişan Kayabölen, Uğur Akcan, Doğancan Özturan, Hivda Ülbeği Polat, Gizem Nur Şahin, Nareg Pinarbasi Degirmenci, Canan Bayraktar, Gizem Söyler, Ehsan Sarayloo, Elif Nurtop, Berna Özer, Gülen Güney-Esken, Tayfun Barlas, Ismail Selim Yildirim, Özlem Doğan, , Tugba Bagci Onder

The paper develops multimeric sACE2 decoys using SunTag or MoonTag systems, showing >100-fold increased SARS-CoV-2 neutralization compared to monomeric sACE2.

Advanced Science · Jul 27, 2022Peer-reviewedMolecular Biology