Author

Julia Tigges

Leibniz Institute of Environmental MedicineORCID 0000-0002-0847-9939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Borchardt· 1 shared Andreas S. ReichertiD· 1 shared Arif DönmeziD· 1 shared Arun Kumar KondadiiD· 1 shared Gerhard FritziD· 1 shared Karl KöhreriD· 1 shared Katharina KochiD· 1 shared Lluís Enjuanes-RuiziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Andrea Borchardt

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1 paper

Recent·Most cited

Preconditioning of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming in iPSC-derived cardiomyocytes linked to mitochondrial dysfunction and impaired cardiac regeneration

Michelle Westerhoff, Nahal Brocke‐Ahmadinejad, Yulia Schaumkessel, Karl Köhrer, Arif Dönmez, Roohallah Ghodrat, Andrea Borchardt, Lluís Enjuanes-Ruiz, Julia Tigges, Katharina Koch, Gerhard Fritz, Arun Kumar Kondadi, Andreas S. Reichert

This study shows that low-dose doxorubicin treatment of human iPSCs causes mitochondrial dysfunction and transcriptional changes that impair cardiac regeneration in derived cardiomyocytes.

bioRxiv · Apr 18, 2025 · PreprintCell Biology