Karl Köhrer

This study identifies Hox4/5 and Hox6/7 genes' roles in forelimb positioning through loss- and gain-of-function experiments in chick embryos, showing Hox4/5 provide permissive cues and Hox6/7 determine limb position.

The paper identifies tertiary lymphoid structures in brain metastases from different cancer types and links their presence to patient survival.

This study identifies the secretome of cardiac fibroblasts in healthy and infarcted mouse hearts, revealing dynamic paracrine factors and potential biomarkers or therapeutic targets.

This study shows that low-dose doxorubicin treatment of human iPSCs causes mitochondrial dysfunction and transcriptional changes that impair cardiac regeneration in derived cardiomyocytes.

The paper investigates how host genetics shape microbiome composition across generations, finding that host genotype has a stronger influence than maternal legacy after the first generation.

The paper shows that AFD neuron dysfunction in C. elegans alters transposable element (TE) expression, with Mirage transposase induction being a consistent phenotype, while Tc1 mutagenesis depends on background factors.

The paper shows MIC26 regulates metabolic pathways by modulating mitochondrial metabolite exchange, with its role reversing under hyperglycemia.

The paper presents a high-quality genome assembly and annotation of Coccomyxa viridis SAG 216-4 using long-read sequencing and Hi-C, resulting in a complete nuclear, mitochondrial, and plastid genome.

This study uses long-read transcriptome sequencing to analyze SF3B1 mutations in CLL and MDS patients, revealing common splicing alterations and their impact on disease prognosis.

The paper shows BATF suppresses IFN I production in pDCs via DC-SCRIPT, revealing a negative feedback loop in antiviral immunity.

The paper shows neurons form direct excitatory synapses with brain-metastatic breast and melanoma cancer cells, supporting metastasis and offering new therapeutic targets.

The paper completes six MHC haplotypes, including DR1, DR4, and structurally variable C4 regions, improving reference panels for immunogenomics analysis.

This study characterizes the transcription factor reservoir and chromatin landscape in naive and TLR9-activated plasmacytoid dendritic cells across multiple timepoints.