Author
Zhenxi Guo
Peking UniversityORCID 0000-0002-0872-0470Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagApproach:experimental assay· 2Organism:bacteria (other)· 1Research Focus:cell-cell communication· 1Research Focus:drug response / drug discovery· 1Research Focus:host-pathogen & immune response· 1Approach:microscopy & imaging analysis· 1Research Focus:protein folding & dynamics· 1Assay:structural biology· 1
Activity by Year
2025-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship2 papers
Recent·Most cited
Architecture and mechanism of a dual-enzyme retron system in prokaryotic immunity
Xuzichao Li, Qiuqiu He, Yanan Liu, Bin Liu, Zhikun Liu, Hong Chen, Shuqin Zhang, Jie Han, Yingcan Liu, Jie Yang, Hang Hubert Yin, Zhenxi Guo, Yong Wei, Zhiyong Yuan, Hongtao Zhu, Heng Zhang
This study characterizes the Ec78 retron system, revealing its dual-enzyme effector complex and the molecular mechanism of phage clearance through cryo-EM structures and functional analysis.
Nature Communications · Dec 7, 2025Peer-reviewedBiochemistry