Author

Merav D. Shmueli

Weizmann Institute of ScienceORCID 0000-0002-9196-7633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron JavittiD· 1 shared Achinoam Shoham· 1 shared Anat Abramov· 1 shared Angham Ibraheem· 1 shared Ariel TennenhouseiD· 1 shared Arseniy A. LoboviD· 1 shared Benjamin F. CravattiD· 1 shared Brenda Arlene SchulmaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aaron JavittORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Targeting proteasome composition reprograms tumor-intrinsic inflammation through selective degradation of STAT1

Merav D. Shmueli, Yongfeng Tao, Ekampreet Singh, Matthias P. Kramer, Anat Abramov, Tuval Aizik, Daoud Sheban, Arseniy A. Lobov, Karin Goldberg, Angham Ibraheem, Ronen Shteinvil, Aaron Javitt, Yishai Levin, Michael A. Schafroth, Daisuke Ogasawara, , Yifat Merbl

This study identifies a small molecule targeting PSME4, which stabilizes STAT1 and reprograms tumor inflammation, suppressing tumor growth by altering cytokine signaling.

bioRxiv · Oct 16, 2026 · PreprintCancer Biology

Asymmetric crosstalk between the BMP and TGFβ pathways resolves signaling ambiguity

Johannes Maria Auth, Inbal Eizenberg-Magar, Omer Erez, Omer Zachar, Merav D. Shmueli, Inbal Zigdon, Achinoam Shoham, Vladimir Mindel, Meytar Asulin Berrebi, Ariel Tennenhouse, Neta Bar-Hai, Rakefet Ben-Yishay, Dana Ishay-Ronen, Yaron E. Antebi

The paper investigates how BMP and TGFβ pathways interact asymmetrically, showing that TGFβ inhibits BMP and BMP enhances TGFβ responses, reducing signaling ambiguity.

bioRxiv · Apr 22, 2026 · PreprintSystems Biology