Author

Jonathan Barra

Mount Sinai HospitalORCID 0000-0003-1060-7407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jose Javier Bravo‐CorderoiD· 2 shared Abigail UchiteleviD· 1 shared Ailen D. Garcia-Santillan· 1 shared Alain NdayisabaiD· 1 shared Alice BuonfiglioliiD· 1 shared Amy L. OlexiD· 1 shared Ashley D. HadjisiD· 1 shared Ashley HarlockiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Jose Javier Bravo‐CorderoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 25, 2025

Tumor cell dissemination is facilitated through regulatory T cell-driven extracellular matrix remodeling

Ailen D. Garcia-Santillan, Jessanne Y. Lichtenberg, He Shen…·Paula D. Bos

This study shows Treg cells remodel the tumor ECM to promote metastasis, with matrisome signatures linked to poor survival in breast cancer.

DOI 10.1101/2025.10.25.684515

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 9, 2025

Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model

Louise Alessandra Mesentier-Louro, Camille Goldman, Sebastian Gaese…·Joel Blanchard

This study develops a human brain tissue model (miBrain) to show that APOE4 astrocytes with cholesterol dysregulation promote α-synuclein pathology through endolysosomal dysfunction.

4 citations

𝕏 PostBluesky