Eli Isael Maciel

The paper develops and validates a 16-plex droplet digital PCR assay for accurate chromosome copy number quantification in C. albicans, showing strong correlation with whole-genome sequencing.

This study identifies Mnl1 as a repressor of azole tolerance in Candida albicans by linking it to sphingolipid metabolism, mitochondrial activity, and PKA signaling.

This study shows planarians develop radiotolerance through repeated ionizing radiation exposure, maintaining genomic integrity and reproductive function.

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.

Electric stimulation restores DNA integrity and cell cycle in planarian tissues damaged by ionizing radiation through Ca2+ signaling and stem cell activation.

This study identifies two C. albicans proteins essential for epithelial infection of planarians and describes a multi-system host response involving stem cells and distinct tissues.