Jessica Raper

ResiPOx, a nanoparticle-delivered TLR7/8 agonist, reprograms tumor-associated myeloid cells to inhibit tumor growth in mouse models of medulloblastoma and diffuse midline glioma.

This study investigates the effects of postnatal Zika virus infection in infant macaques, finding altered neurodevelopment, increased emotional reactivity, and changes in CSF volume and brain structure.

This study investigates the effects of Zika virus infection on infant brain development using single-cell transcriptomics and other methods, identifying disrupted pathways and behavioral changes.

This study investigates how low social status in female rhesus macaques affects reproductive success, hormone levels, and maternal care, finding lower reproductive success and altered estradiol patterns in subordinates.

This study examines how low social status and obesogenic diets affect brain structure in female macaques from infancy to adulthood, finding specific and persistent effects of social rank and transient effects of diet.

This paper develops two epigenetic clocks for rhesus macaques and finds that early life adversity, specifically infant maltreatment, is associated with epigenetic age acceleration.

The paper characterizes two ultrapotent chemogenetic ligands in rhesus macaques, showing good brain penetrance and safety for potential neuroscience research applications.

This study shows that postnatal Zika virus infection in infant macaques leads to long-term behavioral, motor, and cognitive deficits along with structural and functional brain changes.

This study uses chemogenetic tools to transiently inhibit amygdala activity in infant monkeys, showing altered socioemotional behaviors compared to permanent lesions.