Mark A. G. Eldridge

The paper investigates how the primate superior colliculus represents target velocity and position, finding distinct neural geometries for each.

This study compares the retrograde transduction efficiency of four viral vectors in dopaminergic neurons of rhesus monkeys after striatal injection.

The paper identifies a neural representation of action symbols in the ventral premotor cortex of macaque monkeys performing a drawing-like task.

The paper shows that eGlyRs in hippocampal interneurons regulate network activity through developmental and evolutionary conserved mechanisms.

The paper identifies a novel inhibitory interneuron subtype in the dentate gyrus that selectively regulates mossy cell function and shows this pattern is evolutionarily conserved across species.

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

This study shows that visual category learning enhances category separability in monkey inferior temporal cortex by increasing category-selective neurons and prolonging their responses.

This study identifies distinct OFC-subcortical pathways in macaques that support experience-based and inference-based value updating during adaptive decision-making.

The paper shows that opioids suppress inhibition in hippocampal PV-INs but not neocortex across species and development, highlighting conserved and divergent roles in neural circuits.

This paper reevaluates the role of the medial temporal lobe in perception by comparing lesion data across species using a computational model of the ventral visual stream.

This paper describes a surgical method for implanting an Opto-Array in nonhuman primates to enable high-throughput optogenetic stimulation and behavioral testing.

The paper characterizes two ultrapotent chemogenetic ligands in rhesus macaques, showing good brain penetrance and safety for potential neuroscience research applications.

The paper demonstrates fast synaptic-like transmission from striatal cholinergic interneurons to dopaminergic axons, showing axonal integration of synaptic input into spiking.

This study disrupts the connection between the orbitofrontal cortex and rostromedial caudate nucleus in macaques using chemogenetics, showing it impairs reward-based motivational control of goal-directed actions.

This study shows that macaques can categorize animate and inanimate objects using curvilinear image features without training.

The paper develops new DREADD agonists and a PET radiotracer for improved neuronal activity manipulation and noninvasive projection mapping in neurotheranostics.