Author

Lena M. Seyfarth

University of AlabamaORCID 0000-0002-0965-2844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa S. Arnett· 1 shared Benjamin T. KlempiD· 1 shared Brandon J. KimiD· 1 shared Caylah Griffin· 1 shared Erica L. SancheziD· 1 shared Guy A. CaldwelliD· 1 shared Hana ParkiD· 1 shared J. Brucker NourseiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alyssa S. Arnett

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 31, 2026

Impact of Neurons on Group B Streptococcus Interactions at the Blood Brain Barrier

Lena M. Seyfarth, Natalie G Alexander, Alyssa S. Arnett…·Brandon J. Kim

This study shows that neuronal-endothelial communication enhances blood-brain barrier resistance to Group B Streptococcus (GBS) infection by reducing bacterial adherence and invasion.

DOI 10.64898/2026.07.31.741976

humanexperimental assay

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedFeb 6, 2023

Integrated Regulation of Dopaminergic and Epigenetic Effectors of Neuroprotection in Parkinson's Disease Models

J. Brucker Nourse, Shannon N. Russell, Nathan A. Moniz…·Guy A. Caldwell

This study identifies TNK2 as a regulator of dopamine and epigenetic processes in Parkinson's disease, showing that mutations in TNK2 affect neuroprotection through interactions with RNAi and dopamine transport.

14 citations

C. elegansrat

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